Work

Supplementary Figures 1-4 from Synthetic Lethality of PARP Inhibitors in Combination with MYC Blockade Is Independent of BRCA Status in Triple-Negative Breast Cancer

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure 1 Comparison of 24h, 72-h and continuous HTSA in PARPi treated cells Supplementary Figure 2 HTSA versus MTT proliferation assays Supplementary Figure 3 PARPi sensitivity and resistance in breast cancer cells Supplementary Figure 4 Cell-cycle changes following PARP inhibitor treated sensitive (MB436, HCC1806) versus resistant (MB231, SUM149) breast cancer cells.

DOI: 10.1158/0008-5472.22417112

Authors: Jason. P.W. Carey, Cansu Karakas, Tuyen Bui, Xian Chen, Smruthi Vijayaraghavan, Yang Zhao, Jing Wang, Keith Mikule, Jennifer K. Litton, Kelly K. Hunt, Khandan Keyomarsi

Language: English

Topic: PARP inhibition in cancer therapy

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361235740

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