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Supplemental Methods and Supplemenal Figures 1 through 5 from [18F](2S,4R)4-Fluoroglutamine PET Detects Glutamine Pool Size Changes in Triple-Negative Breast Cancer in Response to Glutaminase Inhibition

Year: 2023

Type: supplementary-materials

Abstract: Supplemental Methods. SI-Fig 1 HPLC chromatogram of [18F]4F-Glu and [18F]4F-Gln mixture. SI-Fig 2 Comparison of T/B values obtained by two readers. SI-Fig 3 Comparison of T/B ratios obtained from different tumor ROI methods. SI-Fig 4 Comparison of T/B ratios between single and multiROI approach. SI-Fig 5 Estimation of [18F]4F-Gln distribution volume (DV) by kinetic analyses of PET data.

DOI: 10.1158/0008-5472.22416504

Authors: Rong Zhou, Austin R. Pantel, Shihong Li, Brian P. Lieberman, Karl Ploessl, Hoon Choi, Eric Blankemeyer, Hsiaoju Lee, Hank F. Kung, Robert H. Mach, David A. Mankoff

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361237052

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