Work

Supplementary Figures S1-S5 from Mutational Landscape of Aggressive Prostate Tumors in African American Men

Year: 2023

Type: supplementary-materials

Abstract: Allele frequencies for 128 ancestry informative single nucleotide polymorphisms, with correlations (r values) between Structure model estimates and actual allele frequencies for our 24 African American (AA) patients, plus 146 other AA and 204 European American (EA) samples ; Individual patient admixture proportions from three ancestral populations ; Somatic transition and transversion rates and ratios in our data compared to the TCGA data ; Heatmap showing log2-ratios of tumor versus normal copy number in 100Kb segments across the genome ; Circos plots showing rearrangementsb and copy numberc in the 24 tumor samples, by ETS fusion status .

DOI: 10.1158/0008-5472.22410402

Authors: Karla J. Lindquist, Pamela L. Paris, Thomas J. Hoffmann, Niall J. Cardin, Rémi Kazma, Joel A. Mefford, Jeffrey P. Simko, Vy Ngo, Yalei Chen, Albert M. Levin, Dhananjay Chitale, Brian T. Helfand, William J. Catalona, Benjamin A. Rybicki, John S. Witte

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361237809

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