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Supplementary Video 7 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth

Year: 2023

Type: supplementary-materials

Abstract: MOV file - 1.7MB, Effects of Pi3k Inhibitor LY294002 on Ras-driven basal MEC overgrowth. Representative video depicting an organoid prepared from a Dox-naive basalRas/GFP (K5-rtTA/TGFP/TRAS) mouse cultured in the presence of both Dox and LY294002 in 3D

DOI: 10.1158/0008-5472.22394372

Authors: Kristin A. Plichta, Jessica L. Mathers, Shelley A. Gestl, Adam B. Glick, Edward J. Gunther

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361240405

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