Figures S1-S6, Table S1-S3 from Sustained Adrenergic Signaling Promotes Intratumoral Innervation through BDNF Induction
Year: 2023
Type: other
Abstract: Fig. S1. Sustained adrenergic signaling increases nerve counts in tumors. Fig. S2. Characterization of tumoral innervation. Fig. S3. NE induces BDNF expression. Fig. S4. NE-induced BDNF expression is mediated by ADRB3/Epac/Jnk. Fig. S5. BDNF increases nerve counts. Fig. S6. Adrenergic-mediated mTrkB activation leads to increased in vivo tumor nodule counts. Table S1. Alteration in pathways associated with neuronal growth and function after NE treatment (HeyA8 and SKOV3ip1 cells). Table S2. Association of Clinicopathologic variables with BDNF protein expression. Table S3. Association of Clinicopathologic variables with Nerve Counts.
Authors: Julie K. Allen, Guillermo N. Armaiz-Pena, Archana S. Nagaraja, Nouara C. Sadaoui, Tatiana Ortiz, Robert Dood, Merve Ozcan, Danielle M. Herder, Monika Haemmerle, Kshipra M. Gharpure, Rajesha Rupaimoole, Rebecca A. Previs, Sherry Y. Wu, Sunila Pradeep, Xiaoyun Xu, Hee Dong Han, Behrouz Zand, Heather J. Dalton, Morgan Taylor, Wei Hu, Justin Bottsford-Miller, Myrthala Moreno-Smith, Yu Kang, Lingegowda S. Mangala, Cristian Rodriguez-Aguayo, Vasudha Sehgal, Erika L. Spaeth, Prahlad T. Ram, Stephen T.C. Wong, Frank C. Marini, Gabriel Lopez-Berestein, Steve W. Cole, Susan K. Lutgendorf, Mariella De Biasi, Anil K. Sood
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361256703