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Supplementary Figure 3 from Tumor Suppressor Function of the Plasma Glutathione Peroxidase Gpx3 in Colitis-Associated Carcinoma

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 2275K, Gpx3 expression is downregulated in human colon cancer samples. A) GPX3 expression is significantly downregulated in adenomas and colorectal cancer patients compared with normal adjacent colon tissues. **P<0.01 for each stage relative to normal. B) GPX3 expression in matched human normal and tumor samples. Error bars represent standard deviation of samples performed in duplicate. C) Western blot of GPX3 protein expression in matched human normal and tumor samples. Quantification is presented as fold change intensity controlled for -actin.

DOI: 10.1158/0008-5472.22396673

Authors: Caitlyn W. Barrett, Wei Ning, Xi Chen, Jesse Joshua Smith, Mary K. Washington, Kristina E. Hill, Lori A. Coburn, Richard M. Peek, Rupesh Chaturvedi, Keith T. Wilson, Raymond F. Burk, Christopher S. Williams

Language: English

Topic: Selenium in Biological Systems

Subfield: Nutrition and Dietetics

Field: Nursing

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361258835

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