Supplementary Figures and Figure Legends and Table from Integrin αvβ3 and Fibronectin Upregulate Slug in Cancer Cells to Promote Clot Invasion and Metastasis
Year: 2023
Type: supplementary-materials
Abstract: PDF file, 893K, Supplementary table, figures, figure legends and methods Files in this Data Supplement: � Supplementary Movie 1 - WMV file, 12420 K. Live cell imaging (phase contrast, 10x) of 786-0 cells over 72 hours after embedding in fibrin. � Supplementary Movie 2 - WMV file, 11607 K. Live cell imaging (phase contrast, 10x) of MDA-MB-231 cells over 72 hours after embedding in fibrin. � Supplementary Table, Figures and Legends - PDF file, 893 K. Supplementary Table 1: Clinicopathological data of patients with RCC. Figure S1A: Colony formation of 786-0 and MDA-MB-231 cells. Figure S1B: Cell surface expression of integrin �v�3 analyzed by flow cytometry. Figure S2: Effect of integrin �1 and �3 knockdown. Figure S3: Tumor cell spreading on fibrinogen-coated surface. Figure S4: Effect of fibronectin knockdown. Figure S5: Effect of Slug knockdown or inhibition with the TGF-�RII inhibitor SB431542 (EMD Millipore).
Authors: Lynn M. Knowles, Lisa A. Gurski, Charlotte Engel, James R. Gnarra, Jodi K. Maranchie, Jan Pilch
Language: English
Subfield: Immunology and Allergy
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361258873