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Supplementary Table 1 from RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer

Year: 2023

Type: supplementary-materials

Abstract: PDF file, 64K, Percent tumor volume change after RKI-1447 treatment of ErbB2 mammary tumor transgenic mice. ErbB2 mammary tumor transgenic mice were treated with RKI-1447 as described under Materials and Methods. Percent change in tumor volume was calculated for each tumor using the following formula; (Vf-V0)/V0*100; where V0= Initial volume (at the beginning of treatment) and Vf= Final volume (at the end of treatment).

DOI: 10.1158/0008-5472.22395768

Authors: Ronil A. Patel, Kara D. Forinash, Roberta Pireddu, Ying Sun, Nan Sun, Mathew P. Martin, Ernst Schönbrunn, Nicholas J. Lawrence, Saïd M. Sebti

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361259654

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