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Supplementary Video 2 from Overcoming Limitations in Nanoparticle Drug Delivery: Triggered, Intravascular Release to Improve Drug Penetration into Tumors

Year: 2023

Type: supplementary-materials

Abstract: AVI file - 34.5MB, Real-time intravascular release of doxorubicin from Dox-TSL and subsequent redistribution of drug in B16 melanoma tumor tissue. The video shows drug (red) delivered over the first 20min, at 20x magnification. The eNOS-GFPtg mouse model was used in this experiment, so the blood vessels are green. (Download before playing in IE8)

DOI: 10.1158/0008-5472.22393952

Authors: Ashley A. Manzoor, Lars H. Lindner, Chelsea D. Landon, Ji-Young Park, Andrew J. Simnick, Matthew R. Dreher, Shiva Das, Gabi Hanna, Won Park, Ashutosh Chilkoti, Gerben A. Koning, Timo L.M. ten Hagen, David Needham, Mark W. Dewhirst

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361267685

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