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Author response: Cryo-EM structures of an LRRC8 chimera with native functional properties reveal heptameric assembly

Year: 2022

Type: peer-review

Abstract: The cryo-electron microscopy structures of an LRRC8C chimera with native channel properties reveal the diverse oligomeric assembly and suggest that lipids may play a role in gating in volume-regulated anion channels.

Source: eLife

DOI: 10.7554/elife.82431.sa2

Authors: Hirohide Takahashi, Toshiki Yamada, Jerod S Denton, Kevin Strange, Erkan Karakas

Institutions: Vanderbilt University, Vanderbilt University Medical Center

Language: English

Topic: Ion channel regulation and function

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W4361734327

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