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Supplemental Figure 2 from Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer

Year: 2023

Type: supplementary-materials

Abstract: A. Heat map of lipid metabolites in LCC1 and LCC9 cells transfected with control or GRP78 siRNA and treated with or without TAM. n=6. B. Relative levels of oleic ethanolamide and palmitoyl ethanolamide in LCC1 and LCC9 cells treated with vehicle, TAM, GRP78 siRNA or GRP78 siRNA+TAM. n=6. C. LCC9 cells were treated with 10 nM -1 microM oleic ethanolamide (OEA), and/or various doses (vehicle, 10 nM, 100 nM, 1000 nM) TAM for 6 days. Relative cell density was determined by crystal violet assay. n=4, *p<0.01.

DOI: 10.1158/0008-5472.22408509

Authors: Katherine L. Cook, David R. Soto-Pantoja, Pamela A.G. Clarke, M. Idalia Cruz, Alan Zwart, Anni Wärri, Leena Hilakivi-Clarke, David D. Roberts, Robert Clarke

Language: English

Topic: Cancer, Lipids, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361804951

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