Work

Canine Intestinal Organoids as a Novel In Vitro Model of Intestinal Drug Permeability: A Proof-of-Concept Study

Year: 2023

Type: preprint

Abstract: Submitted to Cells (MDPI) Manuscript Title: Canine Intestinal Organoids as a Novel In Vitro Model of Intestinal Drug Permeability: A Proof-of-Concept Study Dipak K. Sahoo1*, Marilyn N. Martinez2†*, Kimberly Dao3, Vojtech Gabriel4, Christopher Zdyrski3, Albert E. Jergens1, Todd Atherly3, Chelsea Iennarella-Servantez1, Laura E. Burns5, Dwayne Schrunk5, Donna A. Volpe6†, Karin Allenspach1,3 and Jonathan P. Mochel3,4 1Department of Veterinary Clinical Sciences, Iowa State University, Ames, IA, United States. 2Office of New Animal Drug Evaluation, Center for Veterinary Medicine, Food and Drug Administration, Rockville, Maryland, MD, USA. 33D Health Solutions, Iowa State University, Ames, IA, USA. 4Department of Biomedical Sciences, SMART Pharmacology, Iowa State University, Ames, IA, USA. 5Veterinary Diagnostic Laboratory, Iowa State University, Ames, IA, USA. 6Division of Applied Regulatory Science, Office of Clinical Pharmacology, Center for Drug Evaluation and Research, Food and Drug Administration. Silver Spring, Maryland, MD, USA.

Source: Iowa State University Digital Repository (Iowa State University)

DOI: 10.5281/zenodo.7789639

Authors: Sahoo, Dipak K., Martinez, Marilyn N., Dao, Kimberly, Gabriel, Vojtech, Zdyrski, Christopher, Jergens, Albert E., Atherly, Todd, Iennarella-Servantez, Chelsea, Burns, Laura E., Schrunk, Dwayne, Volpe, Donna A., Allenspach, Karin, Mochel, Jonathan P.

Institutions: Iowa State University, Center for Veterinary Medicine, United States Food and Drug Administration, Center for Drug Evaluation and Research

Language: English

Topic: Drug Transport and Resistance Mechanisms

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4361807374

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Related to: 10