Supplementary Figure 1 from Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 133K, Expression and activity of Wee1 is prevalent in neuroblastoma. (A) A secondary panel of neuroblastoma cell lines demonstrated Wee1 expression and activation (evidenced by phospho-Ser642) by western blot. Cdc2 activity was observed in all neuroblastoma lines. (B) A variety of adult cancer lines were tested for Wee1 phosphorylation, and were generally much lower than that seen in neuroblastoma (far right lanes)
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361809989