Work

Supplementary Figure 1 from FLT3L Release by Natural Killer Cells Enhances Response to Radioimmunotherapy in Preclinical Models of HNSCC

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure 1 (A) Flow cytometry analysis of NK cell population expression of NKG2A in MOC2 tumors 3 days after RT; n=3. (B). Flow cytometry analysis of NK cell populations in MOC2 tumors 3 days after RT and anti-NKG2A therapy; n=6. (C) Flow cytometry analysis of CD4 T cell populations in MOC2 tumors 3 days after RT, anti-NKG2A therapy and NK cell depletion with NK1.1 antibody; n=6. (D) MOC2 tumor volumes of C57BL/6 mice treated with RT and isotype control (red line), anti-CD137, anti-CD25, and anti-NKG2A (blue line), anti-CD17 and antiCD25 (black line); n=7.

DOI: 10.1158/1078-0432.22481835

Authors: Thomas E. Bickett, Michael Knitz, Laurel B. Darragh, Shilpa Bhatia, Benjamin Van Court, Jacob Gadwa, Shiv Bhuvane, Miles Piper, Diemmy Nguyen, Hua Tu, Laurel Lenz, Eric T. Clambey, Kevin Barry, Sana D. Karam

Language: English

Topic: Immune Cell Function and Interaction

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361815246

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