Supplementary Figure 4 from FLT3L Release by Natural Killer Cells Enhances Response to Radioimmunotherapy in Preclinical Models of HNSCC
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figure 4 (A) Gating strategy used in flow cytometry analysis analyzing NK46+ CD3-NK cells, CD11c+ MHCII+ DCs, CD3+ CD4+ T cells, and CD3+ CD8+ T cells. (B) Flow cytometry analysis of NK cell populations in blood from WT C57BL/6 mice treated with RT, anti-CD25, and anti-CD137; n=4. (C) Flow cytometry of CD4 T cell populations in tumors from WT C57BL/6 mice treated with RT, anti-CD25, and anti-CD137 and from DEREG mice treated with RT, anti-CD25, antiCD137, and diphtheria toxin (DT); *p{less than or equal to}0.05, ** p{less than or equal to}0.01; n=6. (D) FLT3L present in serum of C57BL6 treated with radiation therapy, anti-CD25, and anti-CD137, and DEREG mice treated with radiation therapy, anti-CD25, anti-CD137, and diphtheria toxin (DT); ** p{less than or equal to}0.01; n=6
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361815536