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Supplementary Figure 3 from FLT3L Release by Natural Killer Cells Enhances Response to Radioimmunotherapy in Preclinical Models of HNSCC

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure 3 (A) MOC2 tumor volumes of mice treated with RT, anti-CD25, and pLEV vehicle control (black line); RT, anti-CD25, and pLEV FLT3L plasmid (green line), and RT + anti-CD25 (red line). n=7. (B) Flow Cytometry analysis of CD8 T cell populations in MOC2 tumors and lymph nodes (LN) of C57 BL/6 mice. MOC2 tumors were harvested 3 days after RT, NK cell depletion and FLT3L therapy; n=6.

DOI: 10.1158/1078-0432.22481829

Authors: Thomas E. Bickett, Michael Knitz, Laurel B. Darragh, Shilpa Bhatia, Benjamin Van Court, Jacob Gadwa, Shiv Bhuvane, Miles Piper, Diemmy Nguyen, Hua Tu, Laurel Lenz, Eric T. Clambey, Kevin Barry, Sana D. Karam

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361815889

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