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Figure S5 from SMAD4 Gene Mutation Renders Pancreatic Cancer Resistance to Radiotherapy through Promotion of Autophagy

Year: 2023

Type: other

Abstract: Figure S5. SMAD4-induced autophagy is partially rescued by ROS scavenger. (A) Panc-1 cells with Smad4 knockdown were treated with NAC, irradiation (IR), or NAC plus IR. Cell lysates were harvested and blotted with different antibodies indicated. (B) Panc-1 cells with Smad4 knockdown were treated with medium (Control), NAC, or CQ. Cell lysates were harvested and blotted with different antibodies as indicated.

DOI: 10.1158/1078-0432.22470182

Authors: Feng Wang, Xiaojun Xia, Chunying Yang, Jianliang Shen, Junhua Mai, Han-Cheon Kim, Dickson Kirui, Ya'an Kang, Jason B. Fleming, Eugene J. Koay, Sankar Mitra, Mauro Ferrari, Haifa Shen

Language: English

Topic: Autophagy in Disease and Therapy

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361817588

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