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Supplementary figure S2 from Drug-Driven Synthetic Lethality: Bypassing Tumor Cell Genetics with a Combination of AsiDNA and PARP Inhibitors

Year: 2023

Type: supplementary-materials

Abstract: Supplementary figure S2. Correlation between sensitivity of tumor cells to AsiDNA and olaparib. Survival was moniored by trypan blue staining and manual counting (6 days after treatment). Survivals are expressed as % of living non treated cells. Correlation analysis between survival to AsiDNA and olaparib was performed using GraphPadPrism5 software and indicates a non significant correlation.

DOI: 10.1158/1078-0432.22465814

Authors: Wael Jdey, Sylvain Thierry, Christophe Russo, Flavien Devun, Muthana Al Abo, Patricia Noguiez-Hellin, Jian-Sheng Sun, Emmanuel Barillot, Andrei Zinovyev, Inna Kuperstein, Yves Pommier, Marie Dutreix

Language: English

Topic: PARP inhibition in cancer therapy

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361818192

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