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Supplementary Tables from FTO-Dependent N6-Methyladenosine Modifications Inhibit Ovarian Cancer Stem Cell Self-Renewal by Blocking cAMP Signaling

Year: 2023

Type: supplementary-materials

Abstract: Supplemental tables include gene lists related to Figure 5, additional experimental data related to Figure S3I, and primers sequence. Table S1. Numbers of spheroids were counted for each cell dilution; Table S2. List of 20 genes that exhibit a significant change between control and FTO-overexpressing OVCAR5 cells in m6A peak levels, and abundance of the corresponding mRNA transcripta; Table S3. List of primers oligonucleotides; Table S4. Summary of the m6A-seq and RNA-seq; Table S5. List of top 50 hypo-methylation & down-regulated genes; Table S6: List of top 50 hypo-methylation &up-regulated genes.

DOI: 10.1158/0008-5472.22426420.v1

Authors: Hao Huang, Yinu Wang, Manoj Kandpal, Guangyuan Zhao, Horacio Cardenas, Yanrong Ji, Anusha Chaparala, Edward J. Tanner, Jianjun Chen, Ramana V. Davuluri, Daniela Matei

Language: English

Topic: RNA modifications and cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361820399

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