Supplementary Tables 1-8 from Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Tables 1-8. Supplementary table 1: Total number of cases and controls in PRACTICAL III and GWAS stage 3 by population and study. Supplementary Table 2: Data information for family history and age at diagnosis/observation. Supplementary Table 3: Grade-specific and family history-specific odds ratios. Supplementary Table 4: PSA levels by genotype in controls. Supplementary Table 5: Age-specific odds ratios. Supplementary Table 6: The results of 29 pair wise interaction of 25 SNPs significant at P <0.05 (29 out of 300 interactions; Bonferroni correction 0.05/300=1.67x10-4). Supplementary Table 7: Estimated odds ratios of PRS percentiles adjusted for age at diagnosis of PrCa (five categories) in a model allowing for an interaction between PRS and Age. Supplementary Table 8: Estimated odds ratios used for estimating absolute risk.
Authors: Ali Amin Al Olama, Sara Benlloch, Antonis C. Antoniou, Graham G. Giles, Gianluca Severi, David E. Neal, Freddie C. Hamdy, Jenny L. Donovan, Kenneth Muir, Johanna Schleutker, Brian E. Henderson, Christopher A. Haiman, Fredrick R. Schumacher, Nora Pashayan, Paul D.P. Pharoah, Elaine A. Ostrander, Janet L. Stanford, Jyotsna Batra, Judith A. Clements, Suzanne K. Chambers, Maren Weischer, Børge G. Nordestgaard, Sue A. Ingles, Karina D. Sorensen, Torben F. Orntoft, Jong Y. Park, Cezary Cybulski, Christiane Maier, Thilo Doerk, Joanne L. Dickinson, Lisa Cannon-Albright, Hermann Brenner, Timothy R. Rebbeck, Charnita Zeigler-Johnson, Tomonori Habuchi, Stephen N. Thibodeau, Kathleen A. Cooney, Pierre O. Chappuis, Pierre Hutter, Radka P. Kaneva, William D. Foulkes, Maurice P. Zeegers, Yong-Jie Lu, Hong-Wei Zhang, Robert Stephenson, Angela Cox, Melissa C. Southey, Amanda B. Spurdle, Liesel FitzGerald, Daniel Leongamornlert, Edward Saunders, Malgorzata Tymrakiewicz, Michelle Guy, Tokhir Dadaev, Sarah J. Little, Koveela Govindasami, Emma Sawyer, Rosemary Wilkinson, Kathleen Herkommer, John L. Hopper, Aritaya Lophatonanon, Antje E. Rinckleb, Zsofia Kote-Jarai, Rosalind A. Eeles, Douglas F. Easton
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361820767