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Supplementary Figure 4 from FOXC2 Expression Links Epithelial–Mesenchymal Transition and Stem Cell Properties in Breast Cancer

Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figure 4 PDF File - 107K, Cells expressing endogenous FOXC2 exhibit increased sensitivity to sunitinib (a) Quantification of HMLE-Snail and (b) SUM159 cell viability expressing either shControl or shFOXC2, following culture for 96 hours in increasing concentrations of sunitinib. Cell viability was assessed using an MTS assay. (c) In vitro quantification of mammospheres formed by cells described above grown in the presence of sunitinib. Data represents the number of mammospheres formed per 1000 cells seeded after 7 days of culture. Error bars indicate SEM. * P<0.05
DOI: 10.1158/0008-5472.22398671.v1
Authors: Brett G. Hollier, Agata A. Tinnirello, Steven J. Werden, Kurt W. Evans, Joseph H. Taube, Tapasree Roy Sarkar, Nathalie Sphyris, Maryam Shariati, Sreedevi V. Kumar, Venkata L. Battula, Jason I. Herschkowitz, Rudy Guerra, Jeffrey T. Chang, Naoyuki Miura, Jeffrey M. Rosen, Sendurai A. Mani
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: gold
OpenAlex ID: W4361833770
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