Work

Supplementary Figures 1-5 from Targeting Pancreatic Cancer Metastasis by Inhibition of Vav1, a Driver of Tumor Cell Invasion

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figures 1-5. Supplementary Figure 1. Vav1 is expressed in a subset of tumor cell lines. Supplementary Figure 2. Azathioprine does not inhibit migration by pancreatic tumor cells. Supplementary Figure 3. Vav1 is expressed in tumors from a genetic model of pancreatic cancer. Supplementary Figure 4. Azathioprine treatment does not impact tumor size in mouse models of pancreatic cancer. Supplementary Figure 5. Azathioprine reduces cell propagation in a Vav1-independent manner.

DOI: 10.1158/0008-5472.22405406.v1

Authors: Gina L. Razidlo, Christopher Magnine, Arthur C. Sletten, Rachel M. Hurley, Luciana L. Almada, Martin E. Fernandez-Zapico, Baoan Ji, Mark A. McNiven

Language: English

Topic: Pancreatic and Hepatic Oncology Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361834067

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