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Supplementary Materials and Methods, Supplementary Tables 1 and 2 and Supplementary Figures 1 through 5 from PTP1B Deficiency Enables the Ability of a High-Fat Diet to Drive the Invasive Character of PTEN-Deficient Prostate Cancers

Year: 2023
Type: supplementary-materials
Abstract: Supplementary Materials and Methods. Table S1: List of the different oligonucleotides used for mouse genotyping. Table S2: Phenotypic evaluation of prostate-specific PTP1B-overexpressing mice. Figure S1: Ptpn1 status does not alter the transition to mPIN in PtenPE-/- mice. Figure S2: Examples of mild and moderate desmoplasia. Figure S3: HFD drives invasive prostate cancer in the AP only in absence of Ptpn1. Figure S4: Ptpn1 status does not modulate mPIN formation in PtenPE+/- mice. Figure S5: Ptpn1 status influences PtenPE-/- phenotype in a dose-dependent manner.
DOI: 10.1158/0008-5472.22409255.v1
Authors: David P. Labbé, Noriko Uetani, Valérie Vinette, Laurent Lessard, Isabelle Aubry, Eva Migon, Jacinthe Sirois, Jody J. Haigh, Louis R. Bégin, Lloyd C. Trotman, Marilène Paquet, Michel L. Tremblay
Language: English
Field: Medicine
Open Access status: gold
OpenAlex ID: W4361834417
Cites: 6
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Related to: 10