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Supplementary Figures from Integrated Genomic Characterization of the Human Immunome in Cancer

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figures 1-10. Figure-S1. Immune score prediction of response to PD-1 immune checkpoint blockade; Figure-S2. Immune mutation burden in cancer; Figure-S3. Transcriptome alteration of immunome in cancer; Figure-S4. Enrichment of differentially expressed genes (DEGs) in immunological gene signatures; Figure-S5. Immune infiltration score in cancer; Figure-S6. Candidate immune responder genes in cancer; Figure-S7. The ROC curves for different signatures in two datasets; Figure-S8. Barplots showing the AUCs of different signatures across 17 datasets; Figure-S9. CNV alteration and QTL of immune-related genes; Figure-S10. QTLs of immune-related genes across cancer types.

DOI: 10.1158/0008-5472.22425787

Authors: Yongsheng Li, Brandon Burgman, Daniel J. McGrail, Ming Sun, Dan Qi, Sachet A. Shukla, Erxi Wu, Anna Capasso, Shiaw-Yih Lin, Catherine J. Wu, S. Gail Eckhardt, Gordon B. Mills, Bo Li, Nidhi Sahni, S. Stephen Yi

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361841589

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