Supplementary Table 1 from Molecular Profiling Establishes Genetic Features Predictive of the Efficacy of the p110β Inhibitor KIN-193
Year: 2023
Type: supplementary-materials
Abstract: A. 67 PTEN-null cell-lines from GDSC. Columns 1:4 contain serial number, Cell-line identifier, KIN-193 Zscore and KIN-193 ID (S: Sensitive; R: Resistance) respectively. B. Association score of 5143 features with KIN-193 efficacy. Negative RNMI score implies strong association with resistance, positive RNMI core implies strong association with sensitivity. Columns 1:3 contain Gene name which is mutated, RNMI score and status in COSMIC database as cancer gene.
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361845502