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Supplementary Figures S1-S5 from Chemoradiotherapy-Induced Upregulation of PD-1 Antagonizes Immunity to HPV-Related Oropharyngeal Cancer

Year: 2023

Type: supplementary-materials

Abstract: All supplementary Figures S1-S5. FIGURE S1. Gating scheme. FIGURE S2. Effect of chemoradiation on circulating immunocytes. FIGURE S3. Intracellular IFN-γ and TNF-α staining in CD8+ and CD4+ T cells. FIGURE S4. Effect of chemoradiotherapy on PD-1 expression on CD8+T cells. FIGURE S5. Baseline PD-1 expression is correlated with post-treatment PD-1 expression on CD4+ T cells.

DOI: 10.1158/0008-5472.22405311.v1

Authors: Falguni Parikh, Dorothée Duluc, Naoko Imai, Amelia Clark, Krzys Misiukiewicz, Marcello Bonomi, Vishal Gupta, Alexis Patsias, Michael Parides, Elizabeth G. Demicco, David Y. Zhang, Seunghee Kim-Schulze, Johnny Kao, Sacha Gnjatic, Sangkon Oh, Marshall R. Posner, Andrew G. Sikora

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361848538

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