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Supplementary Figures S1-S6 from Differentiation and Loss of Malignant Character of Spontaneous Pulmonary Metastases in Patient-Derived Breast Cancer Models

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figures S1-S6. Supplemental Figure S1. The Differentiation scores (Dscore) of primary tumors and lung met-derived tumors. Supplemental Figure S2. miRNA expression in breast tumors. Supplemental Figure S3. Increased miR-138 expression in metastases versus paired primary tumors. Supplemental Figure S4. FISH analysis of miR-138 gene copy number Supplemental Figure S5. Ability of the miR-138 activity signature to predict breast cancer-specific survival. Supplemental Figure S6. Downstream targets of miR-138.

DOI: 10.1158/0008-5472.22405613.v1

Authors: Jessica Bockhorn, Aleix Prat, Ya-Fang Chang, Xia Liu, Simo Huang, Meng Shang, Chika Nwachukwu, Maria J. Gomez-Vega, J. Chuck Harrell, Olufunmilayo I. Olopade, Charles M. Perou, Huiping Liu

Language: English

Topic: MicroRNA in disease regulation

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361848798

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