Work

Supplementary Tables S1-S5 from Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations

Year: 2023

Type: supplementary-materials

Abstract: PIK3CA mutations in breast cancer from the COSMIC database (S1); Predictions by computational algorithms on the consequences of PIK3CA missense mutations (S2); Mutagenic primer and barcode sequences of PIK3CA constructs and HiTMMoB reaction efficiencies (S3); Representative phenotyping for PIK3CA variants (S4); Barcode representation for PIK3CA variants in each sequenced tumor core (S5).

DOI: 10.1158/0008-5472.22406975.v1

Authors: Turgut Dogruluk, Yiu Huen Tsang, Maribel Espitia, Fengju Chen, Tenghui Chen, Zechen Chong, Vivek Appadurai, Armel Dogruluk, Agna Karina Eterovic, Penelope E. Bonnen, Chad J. Creighton, Ken Chen, Gordon B. Mills, Kenneth L. Scott

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361848892

Cites: 5

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Related to: 10