Work

Supplemental Figures S1-S7 from Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer

Year: 2023

Type: supplementary-materials

Abstract: Fbln5 and α5β1 integrin expression pattern in mouse and human (S1); Characterization of KIC and KPC mice (S2); Examination of ROS levels in normal pancreas and NAC-treated KIC and RGE KIC tumors (S3); Reduced microvessel density (MVD) in RGE KIC and RGE KPC tumors compared to KIC and KPC tumors (S4); Examination and quantification of MVD in pancreatic tissues from KIC and RGE KIC, WT and RGE mice (S5); Fbln5 expression in Fbln5 WT, KO and RGE MEFs (S6); NADPH oxidase (Nox) is not the source of ROS induction for RGE MEFs when plated on FN (S7).

DOI: 10.1158/0008-5472.22406943

Authors: Miao Wang, Mary Topalovski, Jason E. Toombs, Christopher M. Wright, Zachary R. Moore, David A. Boothman, Hiromi Yanagisawa, Huamin Wang, Agnieszka Witkiewicz, Diego H. Castrillon, Rolf A. Brekken

Language: English

Topic: Pancreatic and Hepatic Oncology Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361237496

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