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Supplementary Figures from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figures S1-S4 Supplementary Figure S1 Western blots showing knockdown of ArhGAP11A or RacGAP1. Supplementary Figure S2 ArhGAP11A and RacGAP1 are both required for proliferation of HER2-enriched and luminal B breast cancer cell lines. Supplementary Figure S3 ArhGAP11A and RacGAP1 regulate cell spreading. Supplementary Figure S4 Constitutively active Rac1 and Cdc42 do not affect BLBC proliferation.

DOI: 10.1158/0008-5472.22409228.v1

Authors: Campbell D. Lawson, Cheng Fan, Natalia Mitin, Nicole M. Baker, Samuel D. George, David M. Graham, Charles M. Perou, Keith Burridge, Channing J. Der, Kent L. Rossman

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361850142

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