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Supplementary Figure 1 from Tumor Endothelial Markers Define Novel Subsets of Cancer-Specific Circulating Endothelial Cells Associated with Antitumor Efficacy

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 104KB, Quantitative analysis of CTEC and CEC/CEP populations in mouse specimens by flow cytometry. Syto16 (DNA) gate used to exclude apoptotic, necrotic debris and cellular degraded fragments. CECs were characterized as CD31+CD45-VEGFR-2+CD117-, and CEPs as CD31+CD45-VEGFR-2+CD117+. Gating of CD276+ (top) and TEM7+ (bottom) CTECs from a representative animal specimen is shown.

DOI: 10.1158/0008-5472.22398968

Authors: Reza Mehran, Monique Nilsson, Mehrdad Khajavi, Zhiqiang Du, Tina Cascone, Hua Kang Wu, Andrea Cortes, Li Xu, Amado Zurita, Robert Schier, Bernhard Riedel, Randa El-Zein, John V. Heymach

Language: English

Topic: Angiogenesis and VEGF in Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361872992

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