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Supplementary Figure 1 from A Novel Inhibitor of STAT3 Homodimerization Selectively Suppresses STAT3 Activity and Malignant Transformation

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 264K, Figure S1: STAT3-C rescues from S3I-1757 down regulation of STAT3-regulated genes and inhibition of proliferation/survival. MDA-MB-468 cells were transiently transfected with vector or STAT3C then were treated with S3I-1757 as described in Methods. The cells were then processed for western immuno-blotting (A) and for MTT assays (B) as described in Methods.

DOI: 10.1158/0008-5472.22399041

Authors: Xiaolei Zhang, Ying Sun, Roberta Pireddu, Hua Yang, Murali K. Urlam, Harshani R. Lawrence, Wayne C. Guida, Nicholas J. Lawrence, Saïd M. Sebti

Language: English

Topic: Cytokine Signaling Pathways and Interactions

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361873104

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