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Supplemental Figure 2. Cerenkov Light Images of excised organs. from In Vivo Localization of 90Y and 177Lu Radioimmunoconjugates Using Cerenkov Luminescence Imaging in a Disseminated Murine Leukemia Model

Year: 2023

Type: supplementary-materials

Abstract: Supplemental Figure 2. Cerenkov Light Images of excised organs. Groups of 5 mice were given 300 µCi on 100 µg of 90Y-DOTA-30F11 (A), 177Lu-DOTA-30F11 (B), 90Y-DOTA-Rat IgG (C), or 177Lu-DOTA-Rat IgG (D). Groups of mice were harvested and images collected at 4, 24, 48, and 72 hours post-injection, immediately prior to gamma counting of the tissues. By 24 hours post-injection, there was little or no detectable signal in non-target organs and tissues.

DOI: 10.1158/0008-5472.22403349

Authors: Ethan R. Balkin, Aimee Kenoyer, Johnnie J. Orozco, Alexandra Hernandez, Mazyar Shadman, Darrell R. Fisher, Damian J. Green, Mark D. Hylarides, Oliver W. Press, D. Scott Wilbur, John M. Pagel

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361873943

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