Supplementary Figure 6 from PP2A-B55β Antagonizes Cyclin E1 Proteolysis and Promotes Its Dysregulation in Cancer
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 73KB, B55beta expression knockdown inhibits the growth and decreases cyclin E1 protein levels in colorectal cancer cell lines containing hypermethylated PP2R2B alleles (3). A, Growth of HT29 and HCT116 colorectal carcinoma cells transfected with control or B55beta siRNA measured 96 hrs post-transfection. Experiments were performed in triplicate. B, Western blot of cyclin E1 in HT29 cells 48 hrs post-transfection. Ku86 is shown as loading control.
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361874008