Supplementary Figures S1-S9 from Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figures S1-S9. Avocatin B is the most active avocado lipid analogue (S1); Kinetics of avocatin B-induced death (S2); Cell cycle analysis of avocatin B treated TEX cells (S3); Avocatin B increases DCFH-DA and DHE (S4); Avocatin B's activity is neutralized by co-incubation with PEG-SOD (S5); Jurkat T cells cultured in ethidium bromide medium have reduced mitochondria with decreased function (S6); Avocatin B is absent in mitochondria and cytosolic fractions of vehicle control treated TEX cells (S7); Avocatin B calibration curves and estimated concentraiton in cytosolic and mitochondrial fractions (S8); Avocatin B decreases levels of NADH and NADPH and increases ROS in OCI-AML2 cells (S9).
Authors: Eric A. Lee, Leonard Angka, Sarah-Grace Rota, Thomas Hanlon, Andrew Mitchell, Rose Hurren, Xiao Ming Wang, Marcela Gronda, Ezel Boyaci, Barbara Bojko, Mark Minden, Shrivani Sriskanthadevan, Alessandro Datti, Jeffery L. Wrana, Andrea Edginton, Janusz Pawliszyn, Jamie W. Joseph, Joe Quadrilatero, Aaron D. Schimmer, Paul A. Spagnuolo
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361874473