Supplemental Figures 1-8 from mda-7/IL-24 Induces Cell Death in Neuroblastoma through a Novel Mechanism Involving AIF and ATM
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figure 1. Expression of adenoviral receptors in neuroblastoma cells. Supplementary Figure 2. Ad.5/3-CTV induces pro-apoptotic molecules and downregulates anti-apoptotic molecules. Supplementary Figure 3. Ad.5/3-CTV induces caspase-independent cell death in neuroblastoma cells. Supplementary Figure 4. Ad.5/3-CTV enhances p53 levels in neuroblastoma cells. Supplementary Figure 5. Nuclear translocation of γâ^'H2AX in Ad.5/3-CTV-treated neuroblastoma cells. Supplementary Figure 6. Ad.5/3-CTV infection in neuroblastoma cells promotes nuclear translocation of pATM. Supplementary Figure 7. ATM inhibitor rescues neuroblastoma cells from Ad.5/3-CTV-induced cell death. Supplementary Figure 8. Effect of Ad.5/3-CTV on MDA-7/IL-24 and AIF expression in breast cancer and melanoma cells.
Authors: Praveen Bhoopathi, Nathaniel Lee, Anjan K. Pradhan, Xue-Ning Shen, Swadesh K. Das, Devanand Sarkar, Luni Emdad, Paul B. Fisher
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361874492