Work

Supplementary Methods from The Alkylating Chemotherapeutic Temozolomide Induces Metabolic Stress in IDH1-Mutant Cancers and Potentiates NAD+ Depletion–Mediated Cytotoxicity

Year: 2023

Type: supplementary-materials

Abstract: Detailed information regarding Creation of Glioma Tumorsphere Lines, Cell culture and Reagents, IDH1-R132H Cell Line Generation, shRNA and control shRNA Cell line Generation, Western Blot Analyses, Cell Viability, Cytotoxicity Analysis and Clonogenicity assay, PARP activity assessment, NAD+ quantitation, Animal Studies and Immunohistochemistry

DOI: 10.1158/0008-5472.22414464

Authors: Kensuke Tateishi, Fumi Higuchi, Julie J. Miller, Mara V.A. Koerner, Nina Lelic, Ganesh M. Shankar, Shota Tanaka, David E. Fisher, Tracy T. Batchelor, A. John Iafrate, Hiroaki Wakimoto, Andrew S. Chi, Daniel P. Cahill

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361875792

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