Work

Figure S3 from BRD4 Levels Determine the Response of Human Lung Cancer Cells to BET Degraders That Potently Induce Apoptosis through Suppression of Mcl-1

Year: 2023

Type: other

Abstract: Basal levels of SPOP, Bim and Mcl-1 proteins in NSCLC cell lines with varied sensitivities to BET degraders and correlation between BRD4 and Mcl-1 or between Mcl-1 and cell response to ZBC260.

DOI: 10.1158/0008-5472.22423470

Authors: Dan Zong, Jiajia Gu, Giovanna C. Cavalcante, Weilong Yao, Guojing Zhang, Shaomeng Wang, Taofeek K. Owonikoko, Xia He, Shi-Yong Sun

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361877181

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