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Supplementary Figure S6. Ionizing radiation induces micronuclei formation in both WT and STING-/- MEFs. from STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability

Year: 2023

Type: supplementary-materials

Abstract: WT and STING-/- MEFs examined by cytokinesis-block micronucleus (CBMN) assay by treatment with IR, then cytochalasin at 24 hours and then fixed and stained for DNA and mitochondrial/cytoplasmic compartments using Draq5 and MitoTracker Red at 48 hours. Scale bar, 10 µm.

DOI: 10.1158/0008-5472.22423793

Authors: Diana Rose E. Ranoa, Ryan C. Widau, Stephen Mallon, Akash D. Parekh, Claudia M. Nicolae, Xiaona Huang, Michael J. Bolt, Ainhoa Arina, Renate Parry, Stephen J. Kron, George-Lucian Moldovan, Nikolai N. Khodarev, Ralph R. Weichselbaum

Language: English

Topic: interferon and immune responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361877248

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