Work

Supplementary Figure 6 from Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 84K, HT29 and Colo205 parental and PLX-resistant (RC) cell lines subjected to FISH for EGFR. A) Representative fields from each of the 4 cell lines are shown below, with red EGFR probe and green Chr7 centromeric probe. B) FISH scoring confirms HT29RC amplification, compared to centromeric control.

DOI: 10.1158/1078-0432.22445829

Authors: Muling Mao, Feng Tian, John M. Mariadason, Chun C. Tsao, Robert Lemos, Farshid Dayyani, Y.N. Vashisht Gopal, Zhi-Qin Jiang, Ignacio I. Wistuba, Xi M. Tang, William G. Bornman, Gideon Bollag, Gordon B. Mills, Garth Powis, Jayesh Desai, Gary E. Gallick, Michael A. Davies, Scott Kopetz

Language: English

Topic: Colorectal Cancer Treatments and Studies

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361881555

Cites:

Cited by:

Related to: 10