Work

Supplementary Figure 3 from T Lymphocytes Redirected against the Chondroitin Sulfate Proteoglycan-4 Control the Growth of Multiple Solid Tumors both In Vitro and In Vivo

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 179K, CSPG4 mRNA expression levels in normal tissues. Top panel, CSPG4 expression across normal human tissues represented in the Novartis GeneAtlas dataset (http://biogps.org). Values represented are relative and the average of Affymetrix probe sets 214297_at and 204736_s_at. Highlighted are normal tissues for which corresponding normal adjacent tissue data were available in TCGA datasets. Bottom panel, CSPG4 mRNA expression by TCGA in a variety of solid tumors (featured in main Figure 1D) and normal adjacent tissues (the normal tissues being also represented in GeneAtlas), with the cancers showing higher CSPG4 levels over that of the normal samples. Note shown is log2 scale.

DOI: 10.1158/1078-0432.22450251

Authors: Claudia Geldres, Barbara Savoldo, Valentina Hoyos, Ignazio Caruana, Ming Zhang, Eric Yvon, Michele Del Vecchio, Chad J. Creighton, Michael Ittmann, Soldano Ferrone, Gianpietro Dotti

Language: English

Topic: Proteoglycans and glycosaminoglycans research

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361882819

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