Supplementary Figure S5 from Personalized Preclinical Trials in BRAF Inhibitor–Resistant Patient-Derived Xenograft Models Identify Second-Line Combination Therapies
Year: 2023
Type: supplementary-materials
Abstract: A. heat map of complete RPPA data median centered, all tumor grafts untreated. Data are mean of 3 biological replicates, red is up, green is down. B. Principal component analysis (PCA) of median centered data C. heat map of fold change between untreated tumor grafts and on chronic BRAF inhibitor therapy. D. Principal component analysis (PCA) of fold change data.
Authors: Clemens Krepler, Min Xiao, Katrin Sproesser, Patricia A. Brafford, Batool Shannan, Marilda Beqiri, Qin Liu, Wei Xu, Bradley Garman, Katherine L. Nathanson, Xiaowei Xu, Giorgos C. Karakousis, Gordon B. Mills, Yiling Lu, Tamer A. Ahmed, Poulikos I. Poulikakos, Giordano Caponigro, Markus Boehm, Malte Peters, Lynn M. Schuchter, Ashani T. Weeraratna, Meenhard Herlyn
Language: English
Topic: Melanoma and MAPK Pathways
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361884479