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Supplemental Figure 2 from Epithelial–Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor–Mediated Apoptosis in Non–Small Cell Lung Cancer

Year: 2023

Type: supplementary-materials

Abstract: Baseline gene and protein expression levels correlate with sensitivity to PLK1 inhibition in NSCLC cell lines. For NSCLC cell lines sensitive and resistant to all 3 drugs or to GSK461364 alone, baseline mRNA (48,804 probe sets) expression levels were compared using Illumina arrays (A), and baseline protein expression levels were compared using reverse-phase protein arrays (B). FDR, false-discovery rate.

DOI: 10.1158/1078-0432.22458893

Authors: Renata Ferrarotto, Ruchitha Goonatilake, Suk Young Yoo, Pan Tong, Uma Giri, Shaohua Peng, John Minna, Luc Girard, Yuehong Wang, Liguang Wang, Lerong Li, Lixia Diao, David H. Peng, Don L. Gibbons, Bonnie S. Glisson, John V. Heymach, Jing Wang, Lauren A. Byers, Faye M. Johnson

Language: English

Topic: Cancer Cells and Metastasis

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361885061

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