Work

Supplementary Figure S1: Effect of ipilimumab on immune subsets in human melanoma from Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3+ Regulatory T Cells (Tregs) in Human Cancers

Year: 2023

Type: supplementary-materials

Abstract: A) The representative IHC micrographs for CD4+ and CD8+ cells from stage-matched untreated and Ipi-treated metastatic melanoma tumor sample at 10X and 20X magnifications (inset). Paired pre- and post-Ipi treated melanoma tumor samples from one responder (in red) and three non-responders (in black) analyzed by IHC for the presence of B) CD8+ cells and C) FOXP3+ cells.

DOI: 10.1158/1078-0432.22468907

Authors: Anu Sharma, Sumit K. Subudhi, Jorge Blando, Jorge Scutti, Luis Vence, Jennifer Wargo, James P. Allison, Antoni Ribas, Padmanee Sharma

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361886800

Cites:

Cited by:

Related to: 10