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An integrated supplementary document for 3 figures from Role of Platelet-Derived Tgfβ1 in the Progression of Ovarian Cancer

Year: 2023

Type: other

Abstract: Figure S1: Effect of platelet Tgfï�¢1 and ovarian cancer cell Tgfï�¢R1 on the number of tumor nodules in orthotopic murine models of ovarian cancer. Figure S2: Quantification of Tgfï�¢R1 mRNA level by qRT-PCR in IG10 and ID8 murine ovarian cancer cells incubated with scrambled siRNA or human specific hTgfï�¢R1 siRNA in vitro for 48 hours (n=6). Figure S3: Effect of platelet Tgfï�¢1 on proliferation of human ovarian cancer cells in vitro. Platelets isolated from whole blood of mice were coincubated with human ovarian cancer cells (SKOV3ip1, OVCAR432, and CaOV3) and cell proliferation rate was measured by quantifying BrdU incorporations

DOI: 10.1158/1078-0432.22469064

Authors: Qianghua Hu, Takeshi Hisamatsu, Monika Haemmerle, Min Soon Cho, Sunila Pradeep, Rajesha Rupaimoole, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Stephen T.C. Wong, Anil K. Sood, Vahid Afshar-Kharghan

Language: English

Topic: TGF-β signaling in diseases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361886909

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