Supp. Figure 3 from Expression of PD-1 by T Cells in Malignant Glioma Patients Reflects Exhaustion and Activation
Year: 2023
Type: book-review
Abstract: Supplementary Figure 3: Gene expression analysis shows increased transcription of activation and exhaustion genes in the PD-1+ population in glioma TILs and of antigen experienced genes in the PD-1+ population in glioma PBMCs (each dot represents a distinct patient). A) Fold change of various exhaustion markers between PD-1+ and PD-1- cells in glioma TILs and PBMCs. B) Fold change of various activation markers between the PD-1+ and PD-1- cells in glioma TILs and PBMCs. C) Fold change of various memory markers between the PD-1+ and PD-1- cells in glioma TILs and PBMCs.
Authors: Tom B. Davidson, Alexander Lee, Melody Hsu, Shaina Sedighim, Joey Orpilla, Janet Treger, Max Mastall, Saskia Roesch, Carmen Rapp, Mildred Galvez, Aaron Mochizuki, Joseph Antonios, Alejandro Garcia, Nikesh Kotecha, Nicholas Bayless, David Nathanson, Anthony Wang, Richard Everson, William H. Yong, Timothy F. Cloughesy, Linda M. Liau, Christel Herold-Mende, Robert M. Prins
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361887413