Work

Figures S1-S5 from The Proteomic Landscape of Pancreatic Ductal Adenocarcinoma Liver Metastases Identifies Molecular Subtypes and Associations with Clinical Response

Year: 2023

Type: other

Abstract: Figure S1: The complete gene ontology annotation on the Spatial Analysis for Functional Enrichment (SAFE) network for proteins identified by mass spectrometry. Figure S2: Proteomics distinguishes pancreatic cancer metastases in the liver from tumor adjacent liver tissue. Figure S3: The residual variance versus the numbers of protein and sample clusters as defined by the PCA hierarchical clustering model, and the distribution of proteomic subtypes across the 7 batches of PDAC samples. Figure S4: Comparison of proteomic PDAC subtype classification in relation to previously established transcriptomic classification systems. Figure S5: The PLS-DA score plot of the proteomic subtype as determined in the liver metastases proteome versus the primary tumor proteome.

DOI: 10.1158/1078-0432.22474269

Authors: Henry C.-H. Law, Dragana Lagundžin, Emalie J. Clement, Fangfang Qiao, Zachary S. Wagner, Kimiko L. Krieger, Diane Costanzo-Garvey, Thomas C. Caffrey, Jean L. Grem, Dominick J. DiMaio, Paul M. Grandgenett, Leah M. Cook, Kurt W. Fisher, Fang Yu, Michael A. Hollingsworth, Nicholas T. Woods

Language: English

Topic: Pancreatic and Hepatic Oncology Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361888403

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