eFigure5 from Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer
Year: 2023
Type: other
Abstract: Kaplan-Meier curves for overall survival for high TMB {greater than or equal to}7 and {greater than or equal to}10 mutations/Mb and PTEN alterations in non-ICI-treated mTNBC. Overall survival by (A) tumor mutational burden <7 vs. {greater than or equal to}7 mutations/megabase; (B) tumor mutational burden <10 vs. {greater than or equal to}10 mutations/megabase, and (C) PTEN alteration (absent vs. present).
Authors: Romualdo Barroso-Sousa, Tanya E. Keenan, Sonia Pernas, Pedro Exman, Esha Jain, Ana C. Garrido-Castro, Melissa Hughes, Brittany Bychkovsky, Renato Umeton, Janet L. Files, Neal I. Lindeman, Laura E. MacConaill, F. Stephen Hodi, Ian E. Krop, Deborah Dillon, Eric P. Winer, Nikhil Wagle, Nancy U. Lin, Elizabeth A. Mittendorf, Eliezer M. Van Allen, Sara M. Tolaney
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361889641