Work

Supplementary Figure 2 from Tankyrase and the Canonical Wnt Pathway Protect Lung Cancer Cells from EGFR Inhibition

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 235K, Validation of shRNA-mediated knockdown of tankyrase-1 expression, demonstration of enhanced NSCLC cell killing by combined inhibition of tankyrase and EGFR in multiple NSCLC cell lines, and specificity of this synergistic cell killing for NSCLC cells with EGFR activation

DOI: 10.1158/0008-5472.22391511.v1

Authors: Matias Casás-Selves, Jihye Kim, Zhiyong Zhang, Barbara A. Helfrich, Dexiang Gao, Christopher C. Porter, Hannah A. Scarborough, Paul A. Bunn, Daniel C. Chan, Aik Choon Tan, James DeGregori

Language: English

Topic: Wnt/β-catenin signaling in development and cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361894709

Cites:

Cited by:

Related to: 10