Supplementary Figures 1-6 from BMP4 Administration Induces Differentiation of CD133+ Hepatic Cancer Stem Cells, Blocking Their Contributions to Hepatocellular Carcinoma
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 639K, Supplementary Figure 1. CD133 is CSCs surface marker in PLC/PRF/5 cell line. Supplementary Figure 2. BMP4 showed pro-differentiation effect on HCC cell lines. Supplementary Figure 3. Tumorigenicity of CD133+/- HCC cells co-injected with BMP4 or vehicle embedding beads. Supplementary Figure 4. Canonical BMP4 signaling pathway switches on after exogenous BMP4 treatment. Supplementary Figure 5. BMP4 and SMAD6 expression in HCC cell lines. Supplementary Figure 6. Differentiated CSCs displayed enhanced Erk1/2 phosphorylation.
Authors: Lixing Zhang, Hefen Sun, Fangyu Zhao, Ping Lu, Chao Ge, Hong Li, Helei Hou, Mingxia Yan, Taoyang Chen, Guoping Jiang, Haiyang Xie, Ying Cui, Xiaowu Huang, Jia Fan, Ming Yao, Jinjun Li
Language: English
Topic: Cancer Cells and Metastasis
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361895102